Abandoning FEV(1)/FVC < 0.70 to detect airway obstruction: an essential debate but with the right emphasis?

نویسندگان

  • Bas Robberts
  • Tjard Schermer
چکیده

www.chestpubs.org with once daily tiotropium compared with twice daily salmeterol in patients with COPD . Thorax . 2003 ; 58 ( 5 ): 399 404 . 12 . Brusasco V , Hodder R , Miravitlles M , Korducki L , Towse L , Kesten S . Health outcomes following treatment for 6 months with once daily tiotropium compared with twice daily salmeterol in patients with COPD . Thorax . 2006 ; 61 ( 1 ): 91 . 13 . Calverley PM , Kuna P , Monsó E , et al . Beclomethasone/ formoterol in the management of COPD: a randomised controlled trial . Respir Med . 2010 ; 104 ( 12 ): 1858 1868 . 14 . Barr RG , Bluemke DA , Ahmed FS , et al . Percent emphysema, airfl ow obstruction, and impaired left ventricular fi lling . N Engl J Med . 2010 ; 362 ( 3 ): 217 227 . 15 . Quanjer PH , Enright PL , Miller MR , et al ; Pulmonaria Group . Open letter: the need to change the method for defi ning mild airway obstruction . Prim Care Respir J . 2010 ; 19 ( 3 ): 288 291 . 16 . Self-plagiarism: unintentional, harmless, or fraud? Lancet . 2009 ; 374 ( 9691 ): 664 . 17 . Decramer M , Rutten-van Mölken M , Dekhuijzen PNR , et al . Effects of N-acetylcysteine on outcomes in chronic obstructive pulmonary disease (Bronchitis Randomized on NAC CostUtility Study, BRONCUS): a randomised placebo-controlled trial . Lancet . 2005 ; 365 ( 9470 ): 1552 1560 . 18 . Santayana G . Life of Reason: I. Reason in Common Sense . London, England : Archibald Constable ; 1906 .

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Diagnosis of airway obstruction in the elderly: contribution of the SARA study

BACKGROUND The choice between lower limit of normal or fixed value of forced expiratory volume in one second/forced vital capacity ratio (FEV(1)/FVC) < 0.70 as the criterion for confirming airway obstruction is an open issue. In this study, we compared the criteria of lower limit of normal and fixed FEV(1)/FVC for diagnosis of airway obstruction, with a focus on healthy elderly people. METHOD...

متن کامل

[Assessment of the portable COPD-6 device for detecting obstructive airway diseases].

OBJECTIVES To evaluate the agreement and the association with FEV(1), FEV(6) and FEV(1)/FEV(6) measured with the Vitalograph-COPD-6 portable device and the FEV(1), FVC and FEV(1)/FVC by conventional spirometry, and to analyse the validity of this device to detect obstruction. METHODOLOGY A cross-sectional, descriptive, prospective study, that included 180 subjects. A conventional spirometry a...

متن کامل

Acute bronchodilator responsiveness in subjects with and without airflow obstruction in five Latin American cities: the PLATINO study.

BACKGROUND Acute bronchodilator responsiveness is an area of discussion in COPD. No information exists regarding this aspect of the disease from an unselected COPD population. We assessed acute bronchodilator responsiveness and factors influencing it in subjects with and without airway obstruction in an epidemiologic sample. METHODS COPD was defined by GOLD criteria (post-bronchodilator FEV(1...

متن کامل

Forced vital capacity, airway obstruction and survival in a general population sample from the USA.

BACKGROUND Many studies show a link between forced expiratory volume in 1 s (FEV(1)) and survival in the general population and this has been interpreted as a link between airway obstruction and survival. However, the observation that vital capacity is also associated with survival weakens this interpretation. METHODS Data on spirometry and survival were taken from the Atherosclerosis Risk in...

متن کامل

Should forced expiratory volume in six seconds replace forced vital capacity to detect airway obstruction?

It has been suggested that forced expiratory volume in six seconds (FEV(6)) should be substituted for forced vital capacity (FVC) to measure fractions of timed expired volume for airflow obstruction detection. The present authors hypothesised that this recommendation might be questionable because flow after 6 s of forced expiration from more diseased lung units with the longest time constants w...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Chest

دوره 139 5  شماره 

صفحات  -

تاریخ انتشار 2011